Hemochromatosis
Haemochromatosis, also spelled hemochromatosis, is a hereditary disease characterized by improper dietary iron metabolism (making it a iron overload disorder), which causes the accumulation of iron in a number of body tissues Iron accumulation can eventually cause end organ damage, most importantly in the pancreas manifesting as diabetes, and liver failure.
Hereditary hemochromatosis is the concept that known, measurable genetic mutations can be passed from generation to generation and cause iron accumulation, though not all clinical iron overload is associated with known hereditary markers, and not all hereditary markers cause significant iron overload. Semantically, therefore, the condition of a hereditary mutation in the iron metabolism genetic apparatus is not synonymous with clinical iron overload, though the term “hemochromatosis” is used to encompass both these concepts.>
