Galactosemia
Galactosemia is a rare genetic metabolic disorder which affects an individual's ability to properly metabolize the sugar galactose.
Goppert first described the disease in 1917 with its cause as a defect in galactose metabolism being identified by a group led by Herman Kalckar in 1956
Its incidence is about 1 per 47,000 births (classic type). It is much rarer in Japan and much more common in Italy specifically the traveler region.